INOSITOL: A LIPOTROPIC FACTOR

A statistical evaluation of the lipotropic action of inositol.

Inositol as a lipotropic agent in dairy cattle diets.

Fatty liver syndrome or hepatic lipidosis (HL) is a condition thought to contribute to an increased incidence of peripartum disease, reduced response to therapy and decreased fertility in dairy cows. This syndrome is characterized by excess triglyceride (TG) accumulation in the liver and apparent decreased hepatic lipoprotein output. In lactating rats, a similar condition results from feeding a...

Further observations on the lipotropic need for inositol.

Inositol was originally shown to be a lipotropic agent in rats maintained under special conditions (1) ; the animals were depleted of fat and of B vitamins by maintenance for 3 weeks on a fat-free, high carbohydrate diet, and during a subsequent week fat synthesis was promoted by a supplement of B vitamins and a beef liver fraction. Under these conditions the rats developed markedly fatty liver...

The Effect of Dietary Fat on the Lipotropic Action of Inositol

The possibility that choline exerts lipotropic action through its introduction into newly formed lecithin molecules is an attractive hypothesis for which there exists some supporting evidence (l-3). Inositol, which is also a constituent of phospholipid (4, 5), may possibly exert its effect in the same way. McHenry and Patterson (6) have already suggested this possibility. If these two substance...

Comparison of the Lipotropic Effects of Choline, Inositol, and Lipocaic in Rats

In a preliminary communication (1) we reported that inositol would prevent the development !of that type of fatty liver, characterized by a high content of cholesterol, which is produced in rats by the administration of biotin. The lipotropic a,ction of inositol has been studied with other types of fatty livers and has been compared with the effects of two other lipotropic agents, choline and l...